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Reprozyme Manual

Enzymatic Instrument and Equipment Cleaner For the chemical reprocessing of surgical instruments, flexible or rigid endoscopes and devices.

REPROZYME MANUALEnzymatic Instrument and Equipment Cleaner is a bactericidal multi-enzyme detergent concentrate which dissolves and removes proteinaceous and organic material (blood, saliva, mucus, etc.) from the surfaces of instruments and equipment.
REPROZYME MANUAL is available in 2 litre selfdosing measure bottles.
REPROZYME MANUAL is non-foaming (designed as a pre-autoclave or automated system cleaner) and non-corrosive (safe on all metals, plastics, rubbers, etc).
REPROZYME MANUAL can be diluted 1 part in 100 parts water for use as a flushing solution (use recommended machine times) in automatic re-processing machines, ultrasonic baths and other automated instrument cleaning systems.
REPROZYME MANUALcan be diluted at 1 part in 50 parts water for soaking instruments (10 minutes).
REPROZYME MANUAL is manufactured in accordance with Quality Management System accredited to ISO9001:2008.

The imperative of securing absolute cleanliness and high level disinfectionof medical instruments has never been more sharply 
focussed. The Hospital Infection Research Laboratory in Birmingham makes clear that meticulous cleaning of instruments prior to their disinfection is an absolute pre-requisite to their re-processing for future use. This advice is reflected also by the guidelines issued by the British Society of Gastroenterology and the Infection Control Nursing Association. 


  • REPROZYME MANUAL is the most technically advanced ENZYMATIC based cleaner available

  • The REPROZYME MANUALenzymes perform much better at low temperatures and at a wide range of alkaline pH

  • The special multiple enzyme chemistry keeps environmental pollution to a low level

  • Waste product arising from the use of REPROZYME MANUALemerges at close to neutral pH and is readily biodegradable

  • REPROZYME MANUALis not a classified irritant (please read MSDS before using product)

  • Alcohol and preservatives make up the balance in demineralised water to ensure shelf life and free flowing of the complete formulation 


Use of REPROZYME MANUAL in machines and tanks 

Use in low temperature instrument washing
(Dosages may vary and be subject to trial and manufacturer’s recommendation.)
A typical cycle for a single chamber automatic machine might be:

  • Pre-cleanse/rinse with cold water 1- 3 mins

  • Cold water in - heat to 40°C (or approx.)

  • REPROZYME MANUALadded at 1% solution

  • Cleansing temperature around 40–50°C - contact time approx. 5 mins

  • Intermediate rinse (optional)

  • Final rinse with water of suitable quality​

Use in Ultrasonic Chambers
A typical application in ultrasonics might be:

  • Thoroughly pre-cleanse by rinsing under running water and agitating the surface with a small brush (e.g. on dental burrs)

  • Shake off residual water

  • I mmerse in a 2% solution of REPROZYME MANUAL in tap water

  • Soak for 5 minutes

  • Do not exceed 40°C

  • Remove, rinse and dry prior to autoclave or chemical sterilisation


As a soak solution in non-ultrasonic tank

  • Follow directions for ultrasonic use up to and including preparation of 2%

  • Soak for 10 minutes

  • Remove, rinse and dry prior to autoclave or chemical sterilisation

  • Solution should be changed weekly or if it becomes soiled or cloudy

Material compatibility of REPROZYME MANUALSurgical Instruments

Because of the nature of the product chemistry, sensitive materials are protected while stubborn residues and deposits are removed swiftly and completely. Difficult to clean areas such as joints, saw teeth and threads benefit in particular from the use of REPROZYME MANUAL


Minimally Invasive Surgical Instrument (MISI)

Most cleaning substances find these instruments very problematical because of their intricacy of design. REPROZYME MANUAL really comes into its own on these instruments. Its use is strongly recommended rather than the use of conventional soap/detergent solutions or even surgical scrubs which are not designed for the purpose.


Anesthesia Equipment

Rubber, latex, various plastics can become embrittled if subjected to the wrong type of cleansing agent. REPROZYME MANUALwill not present the same problem.

Aluminium (anodised or plain)

No record of adverse impact noted.

Stainless steels and plastic work surfaces

No record of adverse impact noted.

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